Unless you have a .45 with a threaded barrel and plan to use it........
I have a full size Ti-Rant I bought years ago and use for nothing these days since I don't own a MK23 any more. It's huge, wish I'd bought the "K" (short version) instead before they stopped making it. Nowadays we have modular designs available. Add/subtract. Pass.
.45 cans are bigger diameter, (need taller sights or block the factory out to a greater degree, your choice) meaning with 9mm you have greater internal volume that helps mitigate the amount of gas jet "blow by" as a result of more slop in the tolerances of the baffle stack. If the front cap is removable theoretically you could replace the .45 one with another sized to 9mm.
I've "standardized" to 9mm. No need for anything bigger, no real point to anything smaller. Modern prefragmented/presegmented HP's tailored to the velocity they are launched at have largely put paid to the 9mm vs. .45 arguments, even the gun rags don't do the formerly obligatory once a year article with that title anymore. .40 is dead.
Suppressed I currently use the Thompson Machine Neptune or the Poseidon on a G17/19, depending. I don't care about "quiet-quiet", just quieter than unsuppressed and not needing ear pro. Working on a Walther P4 with chopped barrel setup (P38K barrel is too short just to thread and mount, back cap would impact the frame) just to get as short as I can front to back, and going to give the USP Compact a chance as well, but other than that, its a .22 Ruger Mk4 with Volquartsen threaded upper and OSS can. No need for more. "Downsizing".