The factory optics ready slide is the way to go. HK has made those plentiful on the market and for a fair price. Check Gunbroker and you'll find them as cheap as the low $300's.
If it was me, I'd go with an
Aimpoint ACRO adapter plate and an ACRO red dot. The P-1 is the current model, and their new P-2 is supposed to be on the market within a few months. They're extremely rugged, closed emitter, more robust mounting system than most others, and the battery can be changed externally. All of those features eliminate most of the problems with other red dots.
As an alternative, the Holosun 509T is a solid choice.
Mounting Systems
Some of the common, quality, and rugged pistol RDS on the market include the Trijicon RMR, Holosun 407/507/508T series, and that's about it if we're talking about a serious use gun. There are many others, but the RMR and Holosuns have established themselves as the best of those open emitter types in terms of durability and reliability.
All of the above require threaded holes in the slide or adapter plate to screw the RDS in to. Those RDS models also feature divots in 2 or 4 places on their undersides for fitting on to recoil lugs in the slide or adapter plate. The difficulty with this sort of system is that fitment of the sight to the plate or slide is critical otherwise you have extreme sheer load on the mounting screws since they are perpendicular to the recoil. It's not uncommon for screws to snap, especially if torqued improperly, and then you get a RDS flying towards your face!
Contrast that with the ACRO or Holosun 509T's mounting system of a railed adapter plate a bit like a shrunken weaver rail. Either of these 2 RDS have a cross bolt that fits across a groove in the plate as well as angled "teeth" that grip the plate when tightened. Just like any other rail-mounted RDS for say a carbine.
Emitter Type
Closed vs. open, not much to say. Closed emitters (ACRO and Holosun 509T) are not exposed to the elements. Open emitters (RMR and Holosun 407/507/508) can be blocked by debris, lint, condensation, etc. and affect the visibility of the dot.
Housing Size
Despite all of the jokes about the ACRO and the insistence by some that they're excessively large, they really aren't that big. They're roughly the size of an RMR in terms of overall length and width. It's just that the ACRO is rectangular whereas the RMR is L-shaped. If the size ends up being a deal breaker for some, the Holosun 509T is a suitable alternative in terms of durability and reliability, and it is a decent amount shorter in length.